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Faculty


Joanna Fowler, Adjunct Professor Emeritus (Brookhaven National Laboratory)

Joanna Fowler

B.A., 1963, University of South Florida
Ph.D., 1967 University of Colorado
Postdoctoral Fellow,1968, University of East Anglia, England

BNL
Email: fowler@bnl.gov

Research Summary

Biochemical effects of drugs, aging and selected diseases on the brain

Radiotracer Chemistry and Neuroimaging Program

Brookhaven Center for Imaging and Neuroscience

Awards/Honors

  • Senior Chemist, Brookhaven National Laboratory
  • Jacob Javits Investigator Award in the Neurosciences, 1986, 1993
  • Gustavus John Esselen Award for Chemistry in the Public Interest, 1988
  • Brookhaven Lab's R&D Award, 1994
  • Aebersold Award from the Society of Nuclear Medicine, 1997
  • Francis P. Garvan-John M. Olin Medal, 1998
  • DOE Ernest O. Lawrence Award, 1999

Publications

Volkow ND, Wang GJ, Fowler JS, et al.
Cardiovascular effects of methylphenidate in humans are associated with increases of dopamine in brain and of epinephrine in plasma
PSYCHOPHARMACOLOGY 166 (3): 264-270 MAR 2003

Li ZZ, Ding YS, Gifford A, et al.
Synthesis of structurally identical fluorine-18 and iodine isotope labeling compounds for comparative imaging
BIOCONJUGATE CHEM 14 (2): 287-294 MAR-APR 2003

Schiffer WK, Azmoodeh M, Gerasimov M, et al.
Selegiline potentiates cocaine-induced increases in rodent nucleus accumbens dopamine
SYNAPSE 48 (1): 35-38 APR 2003

Volkow ND, Wang GJ, Maynard L, et al.
Brain dopamine is associated with eating behaviors in humans
INT J EAT DISORDER 33 (2): 136-142 MAR 2003

Wang GJ, Volkow ND, Thanos PK, et al.
Positron emission tomographic evidence of similarity between obesity and drug addiction
PSYCHIAT ANN 33 (2): 104-111 FEB 2003

Fowler JS, Ding YS, Volkow ND
Radiotracers for positron emission tomography imaging
SEMIN NUCL MED 33 (1): 14-27 JAN 2003

Volkow ND, Wang GJ, Maynard L, et al.
Effects of alcohol detoxification on dopamine D2 receptors in alcoholics: a preliminary study
PSYCHIAT RES-NEUROIM 116 (3): 163-172 DEC 30 2002

Fowler JS, Logan J, Wang GJ, et al.
Monoamine oxidase and cigarette smoking
NEUROTOXICOLOGY 24 (1): 75-82 JAN 2003

Goldstein RZ, Volkow ND, Chang L, et al.
The orbitofrontal cortex in methamphetamine addiction: involvement in fear
NEUROREPORT 13 (17): 2253-2257 DEC 3 2002

Fowler JS
Radiotracer chemistry in 2002
J NUCL MED 44 (1): 19N-+ JAN 2003

Volkow ND, Fowler JS, Wang GJ, et al.
Role of dopamine in the therapeutic and reinforcing effects of methylphenidate in humans: results from imaging studies
EUR NEUROPSYCHOPHARM 12 (6): 557-566 DEC 2002

Volkow ND, Fowler JS, Wang GJ, et al.
Role of dopamine, the frontal cortex and memory circuits in drug addiction: Insight from imaging studies
NEUROBIOL LEARN MEM 78 (3): 610-624 NOV 2002

Thanos PK, Taintor NB, Alexoff D, et al.
In vivo comparative Imaging of dopamine D2 knockout and wild-type mice with C-11-raclopride and microPET
J NUCL MED 43 (11): 1570-1577 NOV 2002

Woody CL, Stoll SP, Schlyer DJ, et al.
A study of scintillation beta microprobes
IEEE T NUCL SCI 49 (5): 2208-2212 Part 1 OCT 2002

Logan J, Fowler JS, Ding YS, et al.
Strategy for the formation of parametric images under conditions of low injected radioactivity applied to PET studies with the irreversible monoamine oxidase a tracers [C-11]clorgyline and deuterium-substituted [11C]clorgyline
J CEREBR BLOOD F MET 22 (11): 1367-1376 NOV 2002

Volkow ND, Fowler JS, Wang GJ
Role of dopamine in drug reinforcement and addiction in humans: results from imaging studies
BEHAV PHARMACOL 13 (5-6): 355-366 SEP 2002

Volkow ND, Fowler JS, Wang GJ
Drug reinforcement and addiction in humans: Results from imaging studies
BEHAV PHARMACOL 13 (5-6): 508-508 SEP 2002

Fowler JS
Richard M. Lambrecht
APPL RADIAT ISOTOPES 57 (5): 605-606 NOV 2002

Volkow ND, Wang GJ, Fowler JS, et al.
Brain DA D2 receptors predict reinforcing effects of stimulants in humans: Replication study
SYNAPSE 46 (2): 79-82 NOV 2002

Fowler JS, Logan J, Wang GJ, et al.
PET Imaging of monoamine oxidase B in peripheral organs in humans
J NUCL MED 43 (10): 1331-1338 OCT 2002