Agatha Lyczek

 Advisor: Dr. Markus Seeliger

Understanding how patient-derived resistance mutations affect the process of imatinib binding to Abl kinase

Agatha Lyczek received a BS from Johns Hopkins University where she majored in Chemical & Biomolecular Engineering and researched in a neuroimaging lab. Her research focused on elucidating the therapeutic role of glial progenitor cells as cell therapy for dysmyelinating disorders. Additionally, she worked towards developing clinically translatable imaging tools (i.e. diffusion tensor MRI) for assessing the efficacy of cell transplantation in the CNS. Post graduation, she interned at Biogen, a biotechnology company specializing in developing therapeutics for neurodegenerative disorders. In 2013, she entered Stony Brook's MSTP (MD/PhD) program. She is a graduate student in Dr. Markus Seeliger's lab where she studies drug resistance mutations in BCR-ABL kinase. Her research aims to advance our understanding of resistance mutations towards targeted therapies and will contribute to the development of more effective targeted cancer therapeutics. Agatha is passionate about cats and bikes.

Recent Publications: